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Cancer Detection

Cancer’s hiding place, exposed.

Delivering clarity, confidence, and peace of mind. iCAD’s ProFound Suite of cancer detection solutions are clinically proven to improve breast cancer detection and radiologist performance.

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A screening revolution has arrived. The difference is ProFound. 

Built with the latest in deep-learning, convolutional neural networks, iCAD’s ProFound AI cancer detection products offer high-performing, concurrent-read, cancer-detection and workflow solutions that rapidly and accurately analyzes each 2D or 3D mammogram image, detecting both malignant soft tissue densities and calcifications with unrivaled accuracy.

ProFound Detection

ProFound Detection V4

FDA Cleared

This next-generation AI solution, trained using advanced deep learning convolutional neural networks (CNN), offers advancements in cancer detection and specificity, achieving a 6.3% improved area under the receiver operating characteristic curve (AUC) over prior version, significantly improving the identification of hard-to-find and aggressive cancers while reducing false positives. This fourth-generation version introduces an option for clinicians to incorporate a prior exam into a current exam’s analysis.

Uncovers hidden cancers feared the most while reducing False Positives.

22%

improvement in finding hard-to-find cancers

18%

improvement in cases with no marks

Priors

incorporated into current AI analysis

† Compared to prior version 3.0.

Breast density imaging on a screen

ProFound AI® for Digital Breast Tomosynthesis and 2D Mammography.

DBT: FDA Cleared. CE Marked. Health Canada Licensed.
2D: CE Marked.

Expertly engineered to enhance cancer screening and diagnostics, augment radiologist performance, and improve patient lives, ProFound AI offers concurrent-read, cancer-detection, and workflow solutions that rapidly and accurately analyzes each tomosynthesis image, detecting both malignant soft tissue densities and calcifications with unrivaled accuracy.

Other: EU | FR | DE | ES | IT

breast imaging result

SecondLook® Detection for 2D Mammography

Developed for 2D mammography, SecondLook’s Detection solution automatically marks suspicious lesions, identifying potential cancers and microcalcifications. The solution provides the radiologist with a “second look” which helps detect actionable missed cancers earlier than screening mammography alone, providing workflow enhancements and improved efficiency. 

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Early detection is critical!

When breast cancer is detected early and still localized, the 5-year relative survival rate is 99%,5 according to the American Cancer Society.

 in
women will get breast cancer in her lifetime.
 – %
of cancers are missed when viewing mammogram images.
With AI, even earlier detection is possible!

When a mammogram uses ProFound Breast Health Suite, radiologists can identify potential cancers years earlier.1,2,17 Detecting cancer at the earliest possible localized stage, when treatments work best.

Find cancers earlier, with greater accuracy, and more efficiency.4  

Breast imaging icon

Clinical Confidence

Improve Cancer Detection Rates

Find Cancers Earlier for Better Outcomes

Reduce False Positives

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Operational Efficiencies

Reduce Radiologist Reading Times

Improve AUC Performance

Fast Imaging Processing

Seamless Integrations & Secure Deployment

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Competitive Differentiation

Market Current Technology

Enhance Patient Satisfaction

Align to Quality & Accreditation

Together, we can impact more lives.

We work the way you want to work.

Rapid implementation for a swift go-live.

Flexible & secure deployment options for smooth IT adoption.

Seamless integration within your workflow and systems you trust.

ProFound Detection V4.0

NEW ProFound Detection Version 4.0

Built for Her. Powered for You.

Next generation of Breast AI, engineered to support radiologists with powerful advancements in accuracy and precision.

New FDA Cleared ProFound Detection V4.0

Smarter Breast AI: Focus on the lesions that matter most.

Priors

Prior mammogram incorporated into AI algorithm.

Add a prior mammogram into the analysis of a current mammogram for even more precise results and fewer marks.

Ipsilateral Correlation

Ipsilateral Correlation of marked lesion improves results.

Comparing ipsilateral (CC-MLO) views of a lesion refines the score based on correlating matching and non-matching observations between views.

Find more cancers

Find more cancers with fewer false positives.

V4 improves accuracy and precision, particularly for challenging cancer cases. Compared to ProFound AI Detection V3.

Schedule Upgrade to ProFound Detection V4

How the Algorithm works.

The ProFound AI algorithm is a highly accurate and clinically proven early cancer detection tool designed to be used concurrently while reading mammogram images. The algorithm has undergone extensive training using one of the most comprehensive 3D image datasets available.

Developed from: 

  • 20M+ million training images 
  • 88,000 training casess
  • 13,500 biopsied cancers
  • 130 contributing centers ensuring data diversity 

A comprehensive ally to cancer detection:

Powered by deep-learning technology, the algorithm leverages convolutional neural networks for image processing and pattern recognition. It meticulously examines mammography slices to localize, segment, and classify areas that warrant attention. Suspicious structures, such as densities (masses, architectural distortions, and asymmetries), as well as clusters of calcifications, are pinpointed using a sophisticated contouring technique.

Example of ProFound Scorecard

Lesion Score

Localized Lesion Marks and Overall Case Score.

A lesion mark outlines an area of concern (masses or calcifications) to be evaluated. Each lesion gets its own score, based on how similar the detection is to known cancerous lesions in the ProFound Detection training database.

Additionally, the whole exam is given a Case Score. This information is instrumental in helping radiologists manage their workload, make informed clinical decisions, and avoid burnout through streamlined workflows.

Scores represent a relative level of concern or suspicion and are not intended to be clinically used for the probability of cancer.

ProFound Interoperability.

Flexible deployment with unmatched speed, scalability, and security.

ProFound Cloud

ProFound Cloud

ProFound Cloud

Your
Cloud

ProFound On Premises

ProFound
On-Premises

50+ PACS & 94 versions | 2D & 3D OEM manufacturers | AI platform providers & workflow systems

We work the way you want to work.

Rapid implementation for a swift go-live.

Flexible & secure deployment options for smooth IT adoption.

Seamless integration within your workflow and systems you trust.

expert voices

Joining forces against a common enemy.

In the fight against cancer, we’re stronger together. Learn why our customers believe that our solutions are the secret weapon for cancer detection and treatment.

Angela Fried headshot

After a year of using it, I’ve come to an eye-opening realization: ProFound AI is looking at things that we clinicians don’t necessarily recognize as signs of cancer. For example, the technology flagged a few cases last year that didn’t appear visibly as signs of cancer at the time, but when the patient returned this year, there’s definitely a cancer there. We’ve really gotten to trust it, and I am hoping that more of those subtle, obscured lesions will be picked up earlier because of this.

Angela Fried
Director of Breast Imaging, SimonMed Imaging
Angela Fried headshot
Angela Fried
Director of Breast Imaging, SimonMed Imaging
Axel Grawingholt headshot

iCAD’s ProFound AI solution has had a significant impact on our workflow. We are able to immediately react if we see something suspicious in a scan alleviating anxiety for our patients. Using the solution will allow us to expand DBT beyond diagnosis because it enables our radiologists to read as many tomosynthesis cases as we currently read with 2D mammography. I consider ProFound AI to be one of the greatest tools in modern radiology.

Dr. Axel Gräwingholt
Radiologie am Theater, Paderborn, Germany
Axel Grawingholt headshot
Dr. Axel Gräwingholt
Radiologie am Theater, Paderborn, Germany
Harold Tanenbaum headshot

iCAD’s ProFound AI for DBT offers a quantum improvement in terms of our efficiency, enabling us to focus on abnormal findings, while reducing the rate of false positives. This is a vital tool for our practice that allows radiologists to zero-in on questionable areas, while reducing reading time and improving our overall confidence in the results.

Dr. Harold Tanenbaum
MD, DABR, MBA, Marine Park Radiology, Brooklyn, NY
Harold Tanenbaum headshot
Dr. Harold Tanenbaum
MD, DABR, MBA, Marine Park Radiology, Brooklyn, NY
Sally Grady headshot

We recently updated our breast screening technology at our facility, and ProFound AI is the icing on the cake. We looked at other AI technologies, but have ultimately found them to be like smoke and mirrors compared to ProFound AI. A game-changing technology, ProFound AI has empowered us to offer world-class, personalized patient care. It is light years ahead of other technologies, which simply cannot measure up. I believe that patients without access to ProFound AI are at a disservice. It has helped make our breast screening program one of the best – not only in the state, but also the world.

Sally Grady
Director, Kettering Health Breast Centers, Kettering Health
Sally Grady headshot
Sally Grady
Director, Kettering Health Breast Centers, Kettering Health
Dr Carolina Walter headshot

ProFound AI offers daily assistance to help me detect breast cancer more effectively and efficiently. It supports me in case assessment and improves my confidence, even while reading challenging cases, such as those with dense breasts.

Carolina Walter
MD Radiologist Medimage (Switzerland)
Dr Carolina Walter headshot
Carolina Walter
MD Radiologist Medimage (Switzerland)
Elena Cauzza headshot

Breast cancer is the most common cancer among women; however, the chances of survival are constantly increasing, especially thanks to technological advances in medical imaging that are improving screening performances. ProFound AI is fully in line with this desire to constantly improve radiologists’ abilities to detect breast cancer as early as possible. This is why I chose to install the new generation of the ProFound AI solution in my medical imaging center dedicated to breast imaging, in order to offer my patients the best possible care.

Elena Cauzza
Radiologist at Radiomedica and xDonna, a mammography and breast diagnosis center in Bellinzona, Switzerland
Elena Cauzza headshot
Elena Cauzza
Radiologist at Radiomedica and xDonna, a mammography and breast diagnosis center in Bellinzona, Switzerland
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Contact Us

Together, we can create a world where cancer can’t hide.

Ready to experience how ProFound can save lives?

3. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpmn/pmn.cfm. Accessed 1-20-23. FDA 510K submissions K182373 (iCAD), K201019 (Hologic) and K193229 (ScreenPoint). 4. Conant EF, Toledano AY, Periaswamy S, Fotin SV, Go J, Boatsman JE, Hoffmeister JW. Improving Accuracy and Efficiency with Concurrent Use of Artificial Intelligence for Digital Breast Tomosynthesis. Radiol Artif Intell. 2019 Jul 31;1(4):e180096. doi: 10.1148/ryai.2019180096. PMID: 32076660; PMCID: PMC6677281. 5. https://www.nationalbreastcancer.org/early-detection-of-breast-cancer. Accessed 11-01-2023.

iCAD data on file. Standalone performance varies by vendor.